Neuropeptide Y Receptor Inhibitors

NPY Y₁ receptor

NPY Y₂ receptor

NPY Y₄ receptor

NPY Y₅ receptor

Neuropeptide Y Receptor Agonists, Antagonists & Activators

Product Name	NPY Y₁ receptor	NPY Y₂ receptor	NPY Y₄ receptor	NPY Y₅ receptor	Purity
BIBO3304	NPY Y₁ receptor				99.95%
BIIE-0246		NPY Y₂ receptor, IC₅₀: 15±3 nM			99.10%
BIBP3226 TFA	rNPY Y₁ receptor, Ki: 1.1 nM				98.55%
[Leu31,Pro34]-Neuropeptide Y(human,rat,mouse) TFA	NPY Y₁ receptor		NPY Y₄ receptor	NPY Y₅ receptor	98.07%
MK-0557				NPY Y₅ receptor	99.84%
RF9	hNPFF1R, Ki: 58 nM	hNPFF2R, Ki: 75 nM			98.14%
Peptide YY (PYY) (3-36), Human		NPY Y₂ receptor			98.57%
[Leu31,Pro34]-Neuropeptide Y (porcine)	NPY Y₁ receptor				98.40%
Neuropeptide Y (3-36) (human, rat)		NPY Y₂ receptor
CYM 9484		NPY Y₂ receptor, IC₅₀: 19 nM			99.43%
BMS-193885	NPY Y₁ receptor				99.08%
RF9 hydrochloride	hNPFF1R, Ki: 58 nM	hNPFF2R, Ki: 75 nM			99.91%
NTNCB hydrochloride	hY₁ receptor, Ki: 16032 nM			hY₅ receptor, Ki: 8 nM	98.07%
SF 11		NPY Y₂ receptor, IC₅₀: 199 nM			99.15%
Neuropeptide Y (13-36), amide, human		NPY Y₂ receptor			98.48%
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide	hY₁ receptor, IC₅₀: 530 nM	hY₂ receptor, IC₅₀: >500 nM	hY₄ receptor, IC₅₀: 51 nM	hY₅ receptor, IC₅₀: 0.24 nM	99.25%
JNJ-5207787		human Y₂ receptor, pIC₅₀: 7.0 rat Y₂ receptor, pIC₅₀: 7.1			≥98.0%
Neuropeptide Y5 receptor ligand-1				NPY Y₅ receptor	≥98.0%
[D-Trp34]-Neuropeptide Y				NPY Y₅ receptor	99.11%
(Leu31,Pro34)-Peptide YY (human) (TFA)	NPY Y₁ receptor, Kd: 1 nM	NPY Y₂ receptor, Kd: 670 nM			99.96%
(Leu31,Pro34)-Peptide YY (human)	NPY Y₁ receptor, Kd: 1.0 nM	NPY Y₂ receptor, Kd: 670 nM
Y1R probe-1	NPY Y₁ receptor
[Leu31,Pro34]-Neuropeptide Y (human,rat)	NPY Y₁ receptor		NPY Y₄ receptor	NPY Y₅ receptor
[D-Arg25]-Neuropeptide Y (human)	NPY Y₁ receptor
BWX 46				NPY Y₅ receptor, IC₅₀: 0.85 nM
(Pro34)-Peptide YY (human)	NPY Y₁ receptor
[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic polypeptide TFA	hY₁ receptor, IC₅₀: 530 nM	hY₂ receptor, IC₅₀: >500 nM	hY₄ receptor, IC₅₀: 51 nM	hY₅ receptor, IC₅₀: 0.24 nM
Neuropeptide Y Y1 receptor antagonist 1	NPY Y₁ receptor, Ki: .19 nM
Peptide YY (pig)		NPY Y₂ receptor
(R)-JNJ-31020028		human Y₂ receptor, pIC₅₀: 8.07 rat Y₂ receptor, pIC₅₀: 8.22 mouse Y₂ receptor, pIC₅₀: 8.21
GR231118			NPY Y₄ receptor
Lu AA33810				hY₅ receptor, Ki: 1.5 nM	98.3%
Neuropeptide Y (3-36) (porcine)		NPY Y₂ receptor
[D-Trp34]-Neuropeptide Y TFA				NPY Y₅ receptor
J-115814	hY₁ receptor, Ki: 1.4 nM rNPY Y₁ receptor, Ki: 1.8 nM	human Y₂ receptor, Ki: >10000 nM	hY₄ receptor, Ki: 620 nM	hY₅ receptor, Ki: 6000 nM

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